Lectroid.net has a sound post on the three pillars of moving the newspaper more effectively to a Web-centric newsroom: staffing, design and workflow.
Key is the principle that newsroom discussion and effort on content needs to focus on topics and not on stories.
All of these pillars pose their challenges, and I'd be the first to admit that even understanding them doesn't necessarily ensure success. But it's a good post on the fundamental best practices.